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Modeling and simulation of droplet translocation and fission by electrowetting-on-dielectrics (EWOD)

Nathan HOWELL, Weihua LI

《机械工程前沿(英文)》 2010年 第5卷 第4期   页码 376-388 doi: 10.1007/s11465-010-0104-z

摘要: This paper discusses methods of microfluidic droplet actuation by means of electrowetting-on-dielectrics (EWOD) and provides a technique for modeling and simulating a microfluidic device by using the computational fluid dynamics (CFD) program, Flow3D. Digital or droplet microfluidics implies the manipulation of droplets on a scale of nanoliters (10 L) to femtoliters (10 L), as opposed to continuous microfluidics that involve the control of continuous fluid within a channel. The two operations in focus here are droplet translocation (moving) and droplet fission (splitting), in which the pressures and velocities within the droplet are analyzed and compared to existing works, both theoretical and experimental. The variation in the pressure of the leading and trailing faces of a droplet indicates the variation in surface energy—an important parameter that explains how a droplet will move toward a region of higher electric potential. The higher voltage on one side of a droplet reduces surface energy, which leads to an induced pressure drop, thus resulting in fluid motion. Flow3D simulations are for both water and blood droplets at voltages between 50 V and 200 V, and the droplet size, surface properties (Teflon coated), and geometry of the system are kept constant for each operation. Some peculiarities of the simulation are brought to light, such as instabilities of the system to higher voltages and fluids with higher dielectric constants, as well as the creation of a tertiary droplet when the applied voltage causes a large enough force during fission. The force distribution across the droplet provides a general understanding of the electrowetting effect and more specifically allows for a comparison between the effects that different voltages have on the forces at the droplet surface. The droplet position and mean kinetic energy of the droplet are also investigated and compared to other works, proving the dynamics of a droplet motion found here.

关键词: electrowetting-on-dielectrics (EWOD)     electrowetting     microfluidics     droplet translocation     droplet fission     Flow3D     dielectric constant    

A rare case of B-lymphoproliferative disorder with villous lymphocytes harboring t(8;14)(q24;q32) translocation

null

《医学前沿(英文)》 2018年 第12卷 第3期   页码 324-329 doi: 10.1007/s11684-017-0558-z

摘要:

Splenic lymphoma with villous lymphocytes (SLVL) or splenic marginal zone lymphoma with circulating villous lymphocytes is rare, and prolymphocytic transformation of SLVL is rarer. At present, only one case of SLVL with t(8;14)(q24;q32) translocation has been reported. In this study, we report a case of B-lymphoproliferative disorder with villous lymphocytes harboring t(8;14)(q24;q32) chromosome translocation that we inclined to SLVL with a prolymphocytic transformation. A 73-year-old female showed marked hepatosplenomegaly and high lymphocytosis (lymphocytes>200×109/L). The abnormal lymphocytes had short coarse villi and round nuclei with prominent nucleoli. The immunophenotypes showed CD19+, CD20+, HLA-DR+, CD22+, CD5+, Kappa+, CD25dim, CD71dim, Lambda, CD7, CD10, CD23, CD34, CD33, CD13, CD14, CD117, CD64, CD103, and CD11c. The karyotype showed complex abnormality: 46XX,+3,−10, t(8;14)(q24;q32)[11]/46XX[9]. The cytoplasmic projection, immunological characteristics, and trisomy 3 chromosome abnormality supported the diagnosis of SLVL. However, the presence of prominent nucleoli and high lymphocytosis suggested prolymphocytic transformation, probably as a result of t(8,14) chromosome translocation. In this report, we described an unusual case of B-lymphoproliferative disorder with villous lymphocytes harboring t(8;14)(q24;q32) translocation, which could provide help in the diagnosis and differential diagnosis of B-lymphocytic proliferative diseases.

关键词: splenic lymphoma with villous lymphocytes     splenic marginal zone lymphoma     transformation     chromosome translocation    

Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of

null

《医学前沿(英文)》 2017年 第11卷 第3期   页码 440-444 doi: 10.1007/s11684-017-0523-x

摘要:

Philadelphia chromosome-positive acute myeloid leukemia is controversial and difficult to distinguish from the blast phase of chronic myeloid leukemia. As a myeloid neoplasm, rare cases of this leukemia manifest multiple soft-tissue tumors or bone lytic lesions. In this paper, we describe a 49-year-old male patient who had an abrupt onset with sharp chest pain, fever, fatigue, emaciation, and splenomegaly. 18F-fluoro-deoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) result showed diffuse and uneven hypermetabolic lesions in the bone marrow with peripheral bone marrow expansion, multiple soft tissue neoplasms with high 18F-FDG uptake, and lytic bone lesions. Bone marrow smear and biopsy detected aberrant blast cells expressing myeloid rather than lymphoid immunophenotype marker. For the existence of Philadelphia chromosome and BCR-ABL1 fusion gene together with complex chromosome abnormalities, a diagnosis of Philadelphia-positive acute myeloid leukemia was made, although the type (de novo or blast crisis) remained unclear.

关键词: Philadelphia chromosome     acute myeloid leukemia     mass     osteolysis     positron emission tomography    

prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed Philadelphia chromosome-positive

null

《医学前沿(英文)》 2017年 第11卷 第2期   页码 229-238 doi: 10.1007/s11684-017-0506-y

摘要:

A CALLG2008 protocol was developed by the Chinese Acute Lymphoblastic Leukemia Cooperative Group for adult acute lymphoblastic leukemia (ALL). We retrospectively analyzed 153 newly diagnosed adult patients with Philadelphia chromosome (Ph)-positive ALL enrolled into imatinib (400 mg/d) plus CALLG2008 regimen between 2009 and 2015. The median age was 40 years (range, 18–68 years), with 81 (52.3%) males. The overall hematologic complete remission (CR) rate was 96.7% after induction. With a median follow-up of 24.2 months, the estimated 3-year overall survival (OS) and event-free survival (EFS) rates were 49.5% (95% confidence interval (CI): 38.5%–59.5%) and 49.2% (95% CI: 38.3%–59.2%), respectively. Fifty-eight (36 with haploidentical donor) patients underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) in first CR. Among the patients in CR1 after induction, both the 3-year OS and EFS were significantly better in the allo-HSCT group than in the without allo-HSCT group (73.2%, 95% CI: 58.3%–83.5% vs. 22.2%, 95% CI: 8.7%–39.6% and 66.5%, 95% CI: 50.7%–78.2% vs. 16.1%, 95% CI: 5.1%–32.7%, respectively). Multivariate analysis showed that allo-HSCT and achievement of major molecular response were associated with favorable OS or EFS independently. Interestingly, in the allo-HSCT cohort, the donor type (haploidentical versus matched donors) had no significant impact on EFS or OS. All these results suggested that imatinib plus CALLG2008 was an effective protocol for Ph-positive ALL. Haploidentical donors can also be a reasonable alternative expedient donor pool.

关键词: Philadelphia chromosome     acute lymphoblastic leukemia     imatinib     CALLG2008    

The predictive value of chromosome 8p deletion for metastasis of hepatocellular carcinoma: a summary

QIN Lunxiu, TANG Zhaoyou, GUAN Xinyuan, YE Qinghai, JIA Huliang, REN Ning

《医学前沿(英文)》 2008年 第2卷 第3期   页码 211-215 doi: 10.1007/s11684-008-0041-y

摘要: Hepatocellular carcinoma (HCC) represents an extremely poor prognostic cancer, which is mainly due to the high frequency of metastasis/recurrence after surgical operation. Exploring the molecular mechanisms involved in HCC metastasis could be helpful in the prediction and early diagnosis of HCC recurrence and could also provide new therapeutic targets for HCC metastasis. In the recent decade, we analyzed the genomic aberrations of the clinical specimens, as well as the metastatic models and cell lines of human HCC to identify the genetic markers related to HCC metastasis and to verify their clinical values in the prediction and control of metastasis of HCC. Using the comparative genomic hybridization (CGH) technique, we compared the differences of chromosomal aberrations between primary HCC tumors and their matched metastatic lesions, and found that chromosome 8p deletions might contribute to HCC metastasis. This novel finding was further confirmed by comparison between nude mice models of HCC with different metastatic potentials. By the more sensitive genome-wide microsatellite analysis, 8p deletion was defined to 8p23.3 and 8p11.2, which are two likely regions harboring metastasis-related genes of HCC. Using ‘8p-specific’ microarrays, two novel metastatic suppressors ( and ) were identified, and were proven to suppress invasion and metastasis of HCC. Clinical studies indicate that 8p deletion detected in HCC or circulating plasma DNA of patients is a useful predictor for metastatic recurrence and prognosis, even for patients with early stage HCC. These novel findings are regarded as important advances in the study of the molecular mechanisms of HCC metastasis, which provide not only a holistic view on the molecular cytogenetic bases of HCC metastasis, but also candidate regions for further study to identify metastatic suppressor genes.

关键词: sensitive genome-wide     prediction     genome-wide microsatellite     frequency     Hepatocellular carcinoma    

A bacterial artificial chromosome-based physical map of

Yuhua FU,Zhiqiang XIA,Shujuan WANG,Xin CHEN,Cheng LU,Mingcheng LUO,Hongbin ZHANG,Wenquan WANG

《农业科学与工程前沿(英文)》 2016年 第3卷 第4期   页码 321-329 doi: 10.15302/J-FASE-2016124

摘要: Cassava ( ) is known as the third most important food crop in the tropics and also used for industrial feedstock for biofuels. Two new bacterial artificial chromosome (BAC) libraries were constructed for W14 ( ssp. ), a wild ancestor of domesticated cassava. The libraries were constructed with RI and dIII insertion vectors, respectively. The RI library has 29952 clones with an average insert size of 115 kb, while the dIII library consists of 29952 clones with an average insert of 129 kb. The combined libraries contain a total of 59904 clones with an average insert size of 125 kb, representing approximately 10 × haploid genome equivalents. A total of 29952 clones were fingerprinted and resulted in a cassava physical map composed of 2485 contigs with an average physical length of 336 kb and 2909 singletons, representing approximately 762 Mb of the cassava genome. 5000 clones located at the ends of BAC contigs were selected and sequenced. A total of 6077 SNPs and 231 indels were identified, that covered 459 gene sequences, of which 6 genes were associated with starch and sucrose metabolism. This BAC-based physical map provides valuable tools to understand the genetics and evolution of cassava.

关键词: cassava     BAC library     physical map    

Translocation and biotoxicity of metal (oxide) nanoparticles in the wetland-plant system

《环境科学与工程前沿(英文)》 2021年 第15卷 第6期 doi: 10.1007/s11783-021-1432-4

摘要:

• Aquatic plants are more likely to absorb TiO2 NPs that are beneficial to them.

关键词: Constructed wetlands     Aquatic plants     Nanoparticles     Physiological activity     Biomass    

244对有不良孕产史夫妇初次染色体断裂率检测结果分析

余宏亮,常明秀,曹恒海,薄立伟,王艳丽,吴艳红

《中国工程科学》 2014年 第16卷 第5期   页码 67-69

摘要:

为了了解有不良孕产史夫妇的染色体断裂率的发生情况,笔者对来河南省人口和计划生育科学技术研究院就诊的有不良孕产史夫妇的染色体断裂率分析的检查结果进行统计学分析。分析结果显示:男性患者的就诊年龄平均为29.07 岁,女性患者的就诊年龄平均为28.15 岁,年龄与染色体检测结果间无相关。男性患者中未发现断裂的占男性总数的32.38 %,女性患者中未发现染色体断裂的占女性总数的37.7 %;男性染色体断裂率为1 的占男性总数的38.11 %,女性染色体断裂率为1 的占女性总数的34.43 %;男性染色体断裂率为2 的占男性总数的21.72 %,女性染色体断裂率为2 的占女性总数的23.36 %;男性染色体断裂率为3 的占男性总数的7.79 %,女性染色体断裂率为3 的占女性总数的2.87 %;女性染色体断裂率为4 的占女性总数的0.82 %;女性染色体断裂率为6 的占女性总数的0.41 %;女性染色体断裂率为9 的占女性总数的0.41 %。男性患者的染色体断裂率均值无差别(P>0.05)。男、女患者的染色体断裂率均值在1.01,患者平均年龄为29.53 岁,经检查有染色体断裂占64.96 %。通过研究发现,染色体断裂率增高可能是引起夫妇中发生胎停、流产、胎儿发育不良等不良孕产现象的重要原因之一。

关键词: 不育夫妇     不良孕产     染色体断裂率    

Effects of nano-silicon and common silicon on lead uptake and translocation in two rice cultivars

Jianguo LIU,Hui CAI,Congcong MEI,Mingxin WANG

《环境科学与工程前沿(英文)》 2015年 第9卷 第5期   页码 905-911 doi: 10.1007/s11783-015-0786-x

摘要: The current study investigated the effects of nano-silicon (Si) and common Si on lead (Pb) toxicity, uptake, translocation, and accumulation in the rice cultivars Yangdao 6 and Yu 44 grown in soil containing two different Pb levels (500 mg·kg and 1000 mg·kg ). The results showed that Si application alleviated the toxic effects of Pb on rice growth. Under soil Pb treatments of 500 and 1000 mg·kg , the biomasses of plants supplied with common Si and nano-Si were 1.8%–5.2% and 3.3%–11.8% higher, respectively, than those of plants with no Si supply (control). Compared to the control, Pb concentrations in rice shoots supplied with common Si and nano-Si were reduced by 14.3%–31.4% and 27.6%–54.0%, respectively. Pb concentrations in rice grains treated with common Si and nano-Si decreased by 21.3%–40.9% and 38.6%–64.8%, respectively. Pb translocation factors (TFs) from roots to shoots decreased by 15.0%–29.3% and 25.6%–50.8%, respectively. The TFs from shoots to grains reduced by 8.3%–13.7% and 15.3%–21.1%, respectively, after Si application. The magnitudes of the effects observed on plants decreased in the following order: nano-Si treatment>common Si treatment and high-grain-Pb-accumulating cultivar (Yangdao 6)>low-grain-Pb-accumulating cultivar (Yu 44) and heavy Pb stress (1000 mg·kg )>moderate Pb stress (500 mg·kg )>no Pb treatment. The results of the study indicate that nano-Si is more efficient than common Si in ameliorating the toxic effects of Pb on rice growth, preventing Pb transfer from rice roots to aboveground parts, and blocking Pb accumulation in rice grains, especially in high-Pb-accumulating rice cultivars and in heavily Pb-polluted soils.

关键词: silicon (Si)     lead (Pb)     rice (Oryza sativa L.)     toxicity     accumulation    

Genomic regions associated with the sex-linked inhibitor of dermal melanin in Silkie chicken

Ming TIAN,Rui HAO,Suyun FANG,Yanqiang WANG,Xiaorong GU,Chungang FENG,Xiaoxiang HU,Ning LI

《农业科学与工程前沿(英文)》 2014年 第1卷 第3期   页码 242-249 doi: 10.15302/J-FASE-2014018

摘要: A unique characteristic of the Silkie chicken is its fibromelanosis phenotype. The dermal layer of its skin, its connective tissue and shank dermis are hyperpigmented. This dermal hyperpigmentation phenotype is controlled by the sex-linked inhibitor of dermal melanin gene ( ) and the dominant fibromelanosis allele. This study attempted to confirm the genomic region associated with . By genotyping, was found to be closely linked to the region between GGA_rs16127903 and GGA_rs14685542 (8406919 bp) on chromosome Z, which contains ten functional genes. The expression of these genes was characterized in the embryo and 4 days after hatching and it was concluded that , encoding methylthioadenosinephosphorylase, would be the most likely candidate gene. Finally, target DNA capture and sequence analysis was performed, but no specific SNP(s) was found in the targeted region of the Silkie genome. Further work is necessary to identify the causal mutation located on chromosome Z.

关键词: sex-linked inhibitor of dermal melanin (Id)     Silkie     chromosome Z    

Relationship between heavy metal concentrations of herbaceous plants and soils at four Pb-Zn mining sites in Yunnan, China

Yuan LI , Yanqun ZU , Qixian FANG , Zhaohua GAO , Christian SCHVARTZ ,

《环境科学与工程前沿(英文)》 2009年 第3卷 第3期   页码 325-333 doi: 10.1007/s11783-009-0024-5

摘要: This paper studied the relationship between heavy metal concentrations of herbaceous plants and soils at four Pb-Zn mining sites in Yunnan, China. 50 herbaceous plant samples of 9 plant species from 4 families and 50 soil samples were collected and then ana1yzed for the tota1 concentrations of Pb, Cd, and Zn. The results showed that the average concentrations of Pb, Cd, and Zn in soil samples were 3772.83, 168.81, and 5385.65 mg/kg, respectively. The average concentrations of Pb, Cd, and Zn were 395.68, 28.14, and 1664.20 mg/kg in the shoots, and 924.12, 57.25 , and 1778.75 mg/kg in the roots, respectively. Heterospecific plants at the same site and conspecific plants at various sites had different average levels of Pb, Cd, and Zn, both in the shoots and the roots. Enrichment coefficients of Pb, Cd, and Zn were greater than 1 in 2, 3, and 9 herbaceous plant samples, respectively. Translocation factors of Pb, Cd, and Zn were greater than 1 in 10, 17, and 25 herbaceous plant samples, respectively. In all 50 samples, the concentrations of Pb, Cd, and Zn between the shoots and the roots, the shoots, and the soils, and the roots and the soils had significant positive relationships.

关键词: Pb     Cd     Zn     herbaceous plants     Pb-Zn mining areas     enrichment coefficient     translocation factor    

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia

Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen

《医学前沿(英文)》 2021年 第15卷 第3期   页码 347-371 doi: 10.1007/s11684-020-0821-6

摘要: B-cell precursor acute lymphoblastic leukemia (BCP-ALL) is characterized by genetic alterations with high heterogeneity. Precise subtypes with distinct genomic and/or gene expression patterns have been recently revealed using high-throughput sequencing technology. Most of these profiles are associated with recurrent non-overlapping rearrangements or hotspot point mutations that are analogous to the established subtypes, such as rearrangements, rearrangements, rearrangements, rearrangements, / and/or rearrangements, like gene expression, PAX5alt (diverse alterations, including rearrangements, intragenic amplifications, or mutations), and hotspot mutations PAX5 (p.Pro80Arg) with biallelic alterations, IKZF1 (p.Asn159Tyr), and ZEB2 (p.His1038Arg). These molecular subtypes could be classified by gene expression patterns with RNA-seq technology. Refined molecular classification greatly improved the treatment strategy. Multiagent therapy regimens, including target inhibitors (e.g., imatinib), immunomodulators, monoclonal antibodies, and chimeric antigen receptor T-cell (CAR-T) therapy, are transforming the clinical practice from chemotherapy drugs to personalized medicine in the field of risk-directed disease management. We provide an update on our knowledge of emerging molecular subtypes and therapeutic targets in BCP-ALL.

关键词: BCP-ALL     subtypes     translocation     aneuploidy     sequence mutations    

Expression of recombinant human butyrylcholinesterase in the milk of transgenic mice

Dan LU,Shengzhe SHANG,Shen LIU,Ying WU,Fangfang WU,Tan TAN,Qiuyan LI,Yunping DAI,Xiaoxiang HU,Yaofeng ZHAO,Ning LI

《农业科学与工程前沿(英文)》 2014年 第1卷 第3期   页码 179-184 doi: 10.15302/J-FASE-2014020

摘要: Butyrylcholinesterase (BCHE) is a natural bioscavenger that protects humans against organophosphate toxicity. Due to the limited yield of human BCHE (hBCHE) when purifying from human plasma, it is necessary to find an alternative method to produce this protein. One potential method is to produce transgenic livestock that make modified milk containing high concentration of hBCHE. In this study, we cloned the gene into a human lactoferrin (hLF) bacterial artificial chromosome (BAC) construct to make a hLF-hBCHE BAC construct. Subsequently, we injected the BAC construct into pronuclei of mouse fertilized embryos and generated transgenic mice. Expression analysis showed that recombinant hBCHE (rhBCHE) was expressed efficiently in the mammary gland of the transgenic mice and the concentration of rhBCHE in the milk of individual mice ranged from 76±12 to 159±28 mg·L . Protein function tests showed that rhBCHE has the same enzymatic activity as the native hBCHE. Our results pave the way for making transgenic livestock to produce large quantities of rhBCHE.

关键词: recombinant human butyrylcholinesterase (rhBCHE)     human lactoferrin bacterial artificial chromosome (hLF BAC)     transgenic mice     milk    

肠道不同解剖部位的菌群组成及其在结直肠癌中的作用

赵浏阳, 张翔, 左涛, 于君

《工程(英文)》 2017年 第3卷 第1期   页码 90-97 doi: 10.1016/J.ENG.2017.01.012

摘要:

结直肠癌是由遗传突变、表观遗传改变、慢性炎症、饮食和生活方式等多因素引起的多阶段疾病。最新研究表明,肠道菌群是结直肠癌发展过程中的重要参与者。肠道菌群稳态的失调,可通过诱发炎症、调控宿主防御、氧化应激和改变细菌代谢产物等机制促进结直肠癌的发生发展。值得注意的是,肠道横、纵截面上不同解剖部位的驻留菌群有所不同。根据细菌在肠道中定植部位的不同,可将其划分为4 种类型:肠腔共生菌、肠黏膜驻留菌、上皮驻留菌和淋巴组织驻留菌。由于结肠共生细菌的易位与结直肠癌的发展密切相关,结直肠癌相关细菌可有望成为用于结直肠癌诊断的非侵入且准确性高的新型生物标志物。本文旨在总结和概述肠道不同解剖部位中的肠道菌群在结直肠癌发生发展中的作用。

关键词: 菌群     结直肠癌     肠腔共生菌     易位     生物标志物    

pakchoi cultivars with low cadmium accumulation and soil factors that affect their cadmium uptake and translocation

Lin WANG,Yingming XU,Yuebing SUN,Xuefeng LIANG,Dasong LIN

《环境科学与工程前沿(英文)》 2014年 第8卷 第6期   页码 877-887 doi: 10.1007/s11783-014-0676-7

摘要: The selection and use of low-Cd-accumulating cultivar (LCAC) has been proposed as one of the promising approaches in minimizing the entry of Cd in the human food chain. This study suggests a screening criterion of LCACs focusing on food safety. Pot culture and plot experiments were conducted to screen out LCACs from 35 pakchoi cultivars and to identify the crucial soil factors that affect Cd accumulation in LCACs. Results of the pot culture experiment showed that shoot Cd concentrations under the three Cd treatments significantly varied across cultivars. Two cultivars, Hualv 2 and Huajun 2, were identified as LCACs because their shoot Cd concentrations were lower than 0.2 mg·kg under low Cd treatment and high Cd exposure did not affect the biomass of their shoots. The plot experiment further confirmed the consistency and genotypic stability of the low-Cd-accumulating traits of the two LCACs under various soil conditions. Results also showed that soil phosphorus availability was the most important soil factor in the Cd accumulation of pakchoi, which related negatively not only to Cd uptake by root but also to Cd translocation from root to shoot. The total Cd accumulation and translocation rates were lower in the LCACs than in the high-Cd cultivar, suggesting that Cd accumulation in different cultivars is associated with the Cd uptake by root as well as translocation from root to shoot. This study proves the feasibility of the application of the LCAC strategy in pakchoi cultivation to cope with Cd contamination in agricultural soils.

关键词: pakchoi (Brassica chinensis L.)     cadmium contamination     low-cadmium-accumulating cultivar (LCAC)     genotype variation     soil factor     translocation    

标题 作者 时间 类型 操作

Modeling and simulation of droplet translocation and fission by electrowetting-on-dielectrics (EWOD)

Nathan HOWELL, Weihua LI

期刊论文

A rare case of B-lymphoproliferative disorder with villous lymphocytes harboring t(8;14)(q24;q32) translocation

null

期刊论文

Philadelphia chromosome-positive acute myeloid leukemia with masses and osteolytic lesions: finding of

null

期刊论文

prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed Philadelphia chromosome-positive

null

期刊论文

The predictive value of chromosome 8p deletion for metastasis of hepatocellular carcinoma: a summary

QIN Lunxiu, TANG Zhaoyou, GUAN Xinyuan, YE Qinghai, JIA Huliang, REN Ning

期刊论文

A bacterial artificial chromosome-based physical map of

Yuhua FU,Zhiqiang XIA,Shujuan WANG,Xin CHEN,Cheng LU,Mingcheng LUO,Hongbin ZHANG,Wenquan WANG

期刊论文

Translocation and biotoxicity of metal (oxide) nanoparticles in the wetland-plant system

期刊论文

244对有不良孕产史夫妇初次染色体断裂率检测结果分析

余宏亮,常明秀,曹恒海,薄立伟,王艳丽,吴艳红

期刊论文

Effects of nano-silicon and common silicon on lead uptake and translocation in two rice cultivars

Jianguo LIU,Hui CAI,Congcong MEI,Mingxin WANG

期刊论文

Genomic regions associated with the sex-linked inhibitor of dermal melanin in Silkie chicken

Ming TIAN,Rui HAO,Suyun FANG,Yanqiang WANG,Xiaorong GU,Chungang FENG,Xiaoxiang HU,Ning LI

期刊论文

Relationship between heavy metal concentrations of herbaceous plants and soils at four Pb-Zn mining sites in Yunnan, China

Yuan LI , Yanqun ZU , Qixian FANG , Zhaohua GAO , Christian SCHVARTZ ,

期刊论文

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia

Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen

期刊论文

Expression of recombinant human butyrylcholinesterase in the milk of transgenic mice

Dan LU,Shengzhe SHANG,Shen LIU,Ying WU,Fangfang WU,Tan TAN,Qiuyan LI,Yunping DAI,Xiaoxiang HU,Yaofeng ZHAO,Ning LI

期刊论文

肠道不同解剖部位的菌群组成及其在结直肠癌中的作用

赵浏阳, 张翔, 左涛, 于君

期刊论文

pakchoi cultivars with low cadmium accumulation and soil factors that affect their cadmium uptake and translocation

Lin WANG,Yingming XU,Yuebing SUN,Xuefeng LIANG,Dasong LIN

期刊论文